Novel DNA Bis-intercalation by MLN944, a Potent Clinical Bisphenazine Anticancer Drug
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چکیده
منابع مشابه
Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug.
The new bisphenazine anticancer drug MLN944 is a novel cytotoxic agent with exceptional anti-tumor activity against a range of human and murine tumor models both in vitro and in vivo. MLN944 has recently entered Phase I clinical trials. Despite the structural similarity with its parent monophenazine carboxamide and acridine carboxamide anticancer compounds, MLN944 appears to work by a distinct ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m404053200